ED pharmaceuticals.
Tadalafil. Sildenafil. Vardenafil. The PDE5-inhibitor class the US telehealth clinics charge $25 a tab for. Same active. Fraction of the price.
7 SKUs in this category.
Sildenafil 100mg
Sildenafil 100mg. Most-prescribed strength, generic of Viagra. Standard adult dose for established responders. PDE5 inhibition; 4–6 hour window. Take 30–60 minutes before…
Sildenafil 50mg
Sildenafil 50mg. Standard starting dose, generic of Viagra. PDE5 inhibition; arousal-dependent. Most physicians recommend starting here and titrating up or down based…
Tadalafil 10mg
Tadalafil 10mg. On-demand generic of Cialis. PDE5 inhibition; arousal-dependent vascular response. Onset 30–60 minutes; effective window extends up to 36 hours —…
Tadalafil 20mg
Tadalafil 20mg. Most-prescribed strength, generic of Cialis. On-demand protocol; the 36-hour window is what gave this molecule its long-window reputation. Take 30–60…
Tadalafil 40mg
Tadalafil 40mg. Higher-dose generic of Cialis. Beyond the FDA-approved 20mg ceiling; appropriate for physician-titrated patients whose response at standard dose was inadequate.…
Tadalafil 5mg
Tadalafil 5mg. Standard daily-dose generic of Cialis. Continuous low-dose maintenance protocol; PDE5 inhibition stays active rather than on-demand. Onset is gradual; full…
Tadalafil 80mg
Tadalafil 80mg. Highest-strength generic of Cialis available. Not for first-time users. Appropriate for physician-titrated patients past the 40mg dose where lower strengths…
PDE5 inhibition. Smooth-muscle relaxation.
The PDE5 class inhibits the enzyme that breaks down cGMP. Smooth muscle in the corpus cavernosum stays relaxed when blood flow needs it. The mechanism is permissive, not stimulating. Sexual response still required, the drug just removes the gate.
2003
Tadalafil FDA approval
Two decades of clinical use. Mechanism well-documented.
36h
Single-dose window
Daily-low-dose or on-demand. Both protocols backed.
$25 -> $1
Per-tab spread
US telehealth vs Razumna. Same active.
How the molecule reaches you.
| Razumna | Telehealth | In Clinic | |
|---|---|---|---|
| Path | Direct-source, no clinic chair | Clinic chair, Rx, retail pharmacy | In-person consult + Rx |
| Per-tab | From $1 / tab | $2-5 / tab generic | $20-25 / tab brand |
| Privacy | Discreet packaging, crypto payment | Insurance record, telehealth record | In-person record, insurance |
| Protocols | Daily-low-dose or PRN, your call | PRN typical, daily extra step | Depends on prescriber |
When this is not the answer.
PDE5 inhibitors are gating, not causal. If the issue is cardiovascular, hormonal, or psychological at root, the gate alone will not solve it. Get a workup. Use the molecule as one input, not the whole answer.
The ones that actually matter.
Same class, different pharmacokinetics. Tadalafil has the longest window (36h), suits daily-low-dose. Sildenafil onset is faster, window is 4-6h. Vardenafil sits in between.
Both work. Daily-low-dose (2.5-5mg tadalafil) keeps the gate open without timing. On-demand (10-20mg tadalafil, 50-100mg sildenafil) suits situational use. Pick the one that fits your week.
Headache, flushing, nasal congestion most common. Vision-blue tint with sildenafil sometimes. Back pain on tadalafil at higher doses. Persistent issue: stop and re-evaluate.
Do not stack with nitrates. Cardiac conditions: get cleared by your physician first. The molecule is well-studied but it is still a vasoactive drug.
Same molecule. Without the clinic chair.
Tadalafil, sildenafil, vardenafil. Direct-source. Crypto pays 20% less.
Not FDA-approved. WHO-GMP / USP-grade generic pharma. See footer for full disclaimer.